1356826-99-7

Basic information

• Product Name: 4-methylphenyl 6-deoxy-5-O-tosyl-2,3-O-1-methylethylidene-1-thio-α-L-allofuranoside
• Synonyms: 4-methylphenyl 6-deoxy-5-O-tosyl-2,3-O-1-methylethylidene-1-thio-α-L-allofuranoside
• CAS NO: 1356826-99-7
• Molecular Weight: 464.604
• Mol File: 1356826-99-7.mol

Chemical Properties

• CAS DataBase Reference: 4-methylphenyl 6-deoxy-5-O-tosyl-2,3-O-1-methylethylidene-1-thio-α-L-allofuranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methylphenyl 6-deoxy-5-O-tosyl-2,3-O-1-methylethylidene-1-thio-α-L-allofuranoside(1356826-99-7)
• EPA Substance Registry System: 4-methylphenyl 6-deoxy-5-O-tosyl-2,3-O-1-methylethylidene-1-thio-α-L-allofuranoside(1356826-99-7)

Safety Data

• Hazardous Substances Data: 1356826-99-7(Hazardous Substances Data)

Upstream product

• 1356826-94-2 4-methylphenyl 2,3-O-1-methylethylidene-1-thio-β-D-ribopentodialdo-1,4-furanoside 
• 1131610-84-8 p-tolyl 1-thio-β-D-ribofuranoside 
• 1356826-96-4 4-methylphenyl 6-deoxy-2,3-O-1-methylethylidene-1-thio-α-L-allofuranoside 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1356827-02-5 4-methylphenyl 5-azido-5,6-dideoxy-2,3-O-1-methylethylidene-1-thio-β-D-allofuranoside 
• 1375073-82-7 C₁₃H₁₇N₃O₃S 
• 1356826-90-8 5-O-(5-amino-5,6-dideoxy-β-D-allofuranosyl)-paromamine 
• 1356826-93-1 5-O-(5-amino-5,6-dideoxy-β-D-allofuranosyl)-1-N-[(S)-4-amino-2-hydroxy-butanoyl]paromamine 
• 1375073-95-2 6′-(R)-methyl-5-O-(5-amino-5,6-dideoxy-β-D-allofuranosyl)-paromamine 
• 1375073-99-6 6′-(R)-methyl-5-O-(5-amino-5,6-dideoxy-β-D-allofuranosyl)-1-N-[(S)-4-amino-2-hydroxy-butanoyl]-paromamine 

Relevant articles and documents

AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS

A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5'' position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: formula I or a pharmaceutically acceptable salt thereof, wherein R1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.