135690-99-2Relevant academic research and scientific papers
Total synthesis of AI-77-B: Stereoselective hydroxylation of 4-alkenylazetidinones
Broady, Simon D.,Rexhausen, Jost E.,Thomas, Eric J.
, p. 1083 - 1094 (1999)
A stereoselective synthesis of the anti-ulcer compound AI-77-B 1 is described. The 4-formylazetidinone 6 was converted into the 4-(Z)-alkene 23 using a phosphonate condensation, and dihydroxylation using osmium tetroxide and N-methylmorpholine W-oxide gav
Total Synthesis of Al-77-B
Broady, Simon D.,Rexhausen, Jost E.,Thomas, Eric J.
, p. 708 - 710 (2007/10/02)
Stereoselective hydroxylation of the β-lactam ester 8 is a key step in a total synthesis of Al-77-B 1.
