135692-98-7Relevant academic research and scientific papers
Synthesis of a new 1,4-aminoalcohol and its use as catalyst in the enantioselective addition of organozinc to aldehydes
Scarpi, Dina,Galbo, Fabrizio Lo,Guarna, Antonio
, p. 1409 - 1414 (2006)
The synthesis of a new enantiopure, conformationally constrained 1,4-aminoalcohol is reported, starting from commercially available reagents from the chiral pool. This 1,4-aminoalcohol was used as chiral ligand in the addition of Et2Zn to aldehydes (best ee 98%) and in the synthesis of chiral propargylic alcohols (best ee 70%) by alkynylzinc species.
