1356966-82-9Relevant articles and documents
Diverse organo-peptide macrocycles via a fast and catalyst-free oxime/intein-mediated dual ligation
Satyanarayana, Maragani,Vitali, Francesca,Frost, John R.,Fasan, Rudi
, p. 1461 - 1463 (2012/03/26)
Macrocyclic Organo-Peptide Hybrids (MOrPHs) can be prepared from genetically encoded polypeptides via a chemoselective and catalyst-free reaction between a trifunctional oxyamino/amino-thiol synthetic precursor and an intein-fusion protein incorporating a bioorthogonal keto group.