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4',6'-difluoro-2'-hydroxyacetophenone is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1356999-25-1 Structure
  • Basic information

    1. Product Name: 4',6'-difluoro-2'-hydroxyacetophenone
    2. Synonyms: 4',6'-difluoro-2'-hydroxyacetophenone
    3. CAS NO:1356999-25-1
    4. Molecular Formula:
    5. Molecular Weight: 172.131
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1356999-25-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4',6'-difluoro-2'-hydroxyacetophenone(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4',6'-difluoro-2'-hydroxyacetophenone(1356999-25-1)
    11. EPA Substance Registry System: 4',6'-difluoro-2'-hydroxyacetophenone(1356999-25-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1356999-25-1(Hazardous Substances Data)

1356999-25-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1356999-25-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,6,9,9 and 9 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1356999-25:
(9*1)+(8*3)+(7*5)+(6*6)+(5*9)+(4*9)+(3*9)+(2*2)+(1*5)=221
221 % 10 = 1
So 1356999-25-1 is a valid CAS Registry Number.

1356999-25-1Relevant articles and documents

Synthesis and biological evaluation of novel flavonols as potential anti-prostate cancer agents

Britton, Robert G.,Horner-Glister, Emma,Pomenya, Odette A.,Smith, Ewan E.,Denton, Roanne,Jenkins, Paul R.,Steward, William P.,Brown, Karen,Gescher, Andreas,Sale, Stewart

, p. 952 - 958 (2012)

A library of flavonol analogues was synthesised and evaluated as potential anticancer agents against a human prostate cancer cell line, 22rν1. Compounds 3, 8 and 11 (IC50 2.6, 3.3 and 4.0 μM respectively) showed potent cancer cell growth inhibi

Discovery of novel 2-(3-phenylpiperazin-1-yl)-pyrimidin-4-ones as glycogen synthase kinase-3β inhibitors

Usui, Yoshihiro,Uehara, Fumiaki,Hiki, Shinsuke,Watanabe, Kazutoshi,Tanaka, Hiroshi,Shouda, Aya,Yokoshima, Satoshi,Aritomo, Keiichi,Adachi, Takashi,Fukunaga, Kenji,Sunada, Shinji,Nabeno, Mika,Saito, Ken-Ichi,Eguchi, Jun-ichi,Yamagami, Keiji,Asano, Shouichi,Tanaka, Shinji,Yuki, Satoshi,Yoshii, Narihiko,Fujimura, Masatake,Horikawa, Takashi

, p. 3726 - 3732 (2017/07/27)

We herein describe the results of further evolution of glycogen synthase kinase (GSK)-3β inhibitors from our promising compounds containing a 2-phenylmorpholine moiety. Transformation of the morpholine moiety into a piperazine moiety resulted in potent GSK-3β inhibitors. SAR studies focused on the phenyl moiety revealed that a 4-fluoro-2-methoxy group afforded potent inhibitory activity toward GSK-3β. Based on docking studies, new hydrogen bonding between the nitrogen atom of the piperazine moiety and the oxygen atom of the main chain of Gln185 has been indicated, which may contribute to increased activity compared with that of the corresponding phenylmorpholine analogues. Effect of the stereochemistry of the phenylpiperazine moiety is also discussed.

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