135704-07-3Relevant academic research and scientific papers
Structure-Activity Relationships of a Series of 2-Amino-4-thiazole-Containing Renin Inhibitors
Patt, William C.,Hamilton, Harriet W.,Taylor, Michael D.,Ryan, Michael J.,Taylor, David G.,et al.
, p. 2562 - 2572 (2007/10/02)
A series of renin inhibitors was synthesized that contained a 2-amino-4-thiazolyl moiety at the P2 position.These derivatives are potent inhibitors of monkey renin in vitro and are selective in that they only weakly inhibit the closely related
