1357089-61-2Relevant academic research and scientific papers
Facile synthesis of tetracyclic azepine and oxazocine derivatives and their potential as MAPKAP-K2 (MK2) inhibitors
Rao, Ashwin U.,Xiao, Dong,Huang, Xianhai,Zhou, Wei,Fossetta, James,Lundell, Dan,Tian, Fang,Trivedi, Prashant,Aslanian, Robert,Palani, Anandan
, p. 1068 - 1072 (2012)
Facile synthesis of two new series of tetracyclic azepine and oxazocine analogs is described. These analogs were evaluated for their potential as MAPKAP-K2 (MK2) inhibitors and several were found to be potent at inhibiting MK2 with a non-ATP competitive binding mode.
