1357160-72-5 Usage
Uses
Different sources of media describe the Uses of 1357160-72-5 differently. You can refer to the following data:
1. URB 937 is a potent inhibitor of fatty-acid amide hydrolase (FAAH), an intracellular serine hydrolase responsible for the deactivation of the endocannabinoid anandamide. It is actively extruded from t
he central nervous system (CNS), and therefore increases anandamide levels exclusively in peripheral tissues.
2. URB 937 is a potent inhibitor of fatty-acid amide hydrolase (FAAH), an intracellular serine hydrolase responsible for the deactivation of the endocannabinoid anandamide. It is actively extruded from the central nervous system (CNS), and therefore increases anandamide levels exclusively in peripheral tissues.
Check Digit Verification of cas no
The CAS Registry Mumber 1357160-72-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,7,1,6 and 0 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1357160-72:
(9*1)+(8*3)+(7*5)+(6*7)+(5*1)+(4*6)+(3*0)+(2*7)+(1*2)=155
155 % 10 = 5
So 1357160-72-5 is a valid CAS Registry Number.
1357160-72-5Relevant articles and documents
Development of a Multigram synthesis of URB937, a peripherally restricted FAAH inhibitor
Fiorelli, Claudio,Scarpelli, Rita,Piomelli, Daniele,Bandiera, Tiziano
, p. 359 - 367 (2013/06/05)
A new synthetic approach to URB937 was developed starting from the inexpensive and widely available 4-benzyloxyphenol. A reproducible four-step procedure, requiring no chromatographic purifications, was optimized that allowed the preparation of 100 g of URB937 in 45% overall yield.
