1357166-41-6Relevant academic research and scientific papers
Cu-catalyzed fluorination of diaryliodonium salts with KF
Ichiishi, Naoko,Canty, Allan J.,Yates, Brian F.,Sanford, Melanie S.
, p. 5134 - 5137 (2013)
A mild Cu-catalyzed nucleophilic fluorination of unsymmetrical diaryliodonium salts with KF is described. This protocol preferentially fluorinates the smaller aromatic ligand on iodine(III). The reaction exhibits a broad substrate scope and proceeds with high chemoselectivity and functional group tolerance. DFT calculations implicate a CuI/CuIII catalytic cycle.
NAPHTHALENE DERIVATIVE
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Paragraph 0446, (2013/06/27)
The present invention provides compounds which can regulate VCP activity. The present invention provides the compound of formula (I) (R is as defined in the description) or oxides, esters, prodrugs, pharmaceutically acceptable salts or solvates thereof. The compounds can regulate VCP activity, and thus are useful for treating VCP-mediated diseases such as neurodegenerative diseases.
AGENT FOR TREATMENT OF EYE DISEASES
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Paragraph 0272; 0275-0276, (2013/08/15)
The present invention provides agents effective to treat eye diseases, pharmaceutical compositions comprising them, methods for preparing pharmaceuticals for treatment of eye diseases comprising using the agents, use of the agents in manufacture of pharma
