135718-84-2Relevant academic research and scientific papers
Transition Metal-Catalyzed, Chlorine-Transfer Radical Cyclizations of 2-(3-Alken-1-oxy)-2-chloroacetates. Formal Total Synthesis of Avenaciolide and Isoavenaciolide
Udding, Jan H.,Tuijp, Kees (C.) J. M.,Zanden, Marco N. A. van,Hiemstra, Henk,Speckamp, W. Nico
, p. 1993 - 2003 (2007/10/02)
A novel method for the synthesis of functionalized tetrahydrofurans is described.This method involves the treatment of 2-(3-alken-1-oxy)-2-chloroacetates 1 with a catalytic amount of Cu(bpy)Cl in refluxing 1,2-dichloroethane to give good yields of 3-(1-ch
Copper catalyzed chlorine transfer cyclizations of glycine and glycolic acid derivatives
Udding, Jan H.,Hiemstra, Henk,Van Zanden, Marco N. A.,Speckamp, W.Nico
, p. 3123 - 3126 (2007/10/20)
Chloroglycine and chloroglycolic acid derivatives smoothly cyclize in the presence of a catalytic amount of cuprous chloride and 2,2′-bipyridine to produce functionalized proline and 2-tetrahydrofurancarboxylic esters, respectively, in an atom transfer pr
