1357181-45-3

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 1357181-62-4 (Z)-4-ethoxy-3-iodo-4-oxobut-2-enoic acid 

Downstream Products

• 1357181-55-5 4-ethoxycarbonyl-6-(3-thienyl)-1-(p-toluenesulfonyl)-1,6-dihydropyridin-2(3H)-one 
• 1373869-66-9 C₁₉H₁₉NO₅S₂ 

Relevant academic research and scientific papers

New type of azacyclization: Thermal preparation of 4,6-disubstituted 2-piperidinone from N-sulfonyldienamide and its substituent effect

The thermal 6-endo cyclization of N-sulfonyl-2,4-dienamide compounds to produce 4,6-disubstituted 2-piperidinone is described. The observed remarkable substituent effect due to the N-sulfonyl and C3 ethoxycarbonyl groups for acceleration of this 6-endo cy

Palladium-catalyzed asymmetric 6-endo cyclization of dienamides with substituent-driven activation

Chiral 2-piperidinone compounds with various C-6 substituents were successfully synthesized via a Pd-catalyzed asymmetric 6-endo cyclization of dienamides, which were evidently activated by both N-p-toluenesulfonyl and C-3 ester substituents.