1357181-75-9Relevant academic research and scientific papers
New type of azacyclization: Thermal preparation of 4,6-disubstituted 2-piperidinone from N-sulfonyldienamide and its substituent effect
Maekawa, Yuya,Sakaguchi, Taku,Tsuchikawa, Hiroshi,Katsumura, Shigeo
, p. 837 - 841 (2012/03/09)
The thermal 6-endo cyclization of N-sulfonyl-2,4-dienamide compounds to produce 4,6-disubstituted 2-piperidinone is described. The observed remarkable substituent effect due to the N-sulfonyl and C3 ethoxycarbonyl groups for acceleration of this 6-endo cy
