1357271-45-4Relevant academic research and scientific papers
NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY
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Page/Page column 63-64, (2020/01/24)
The present invention relates to bicyclic compounds (e.g. indoles) containing a sulfonyl moiety, which bind to the liver X receptor (LXRα and/or LΧΚβ) and act preferably as inverse agonists of LXR.
Synthesis of 3,3-disubstituted α-tetralones by rhodium-catalysed reaction of 1-(2-haloaryl)cyclobutanols
Ishida, Naoki,Sawano, Shota,Murakami, Masahiro
supporting information; experimental part, p. 1973 - 1975 (2012/04/10)
The rhodium-catalysed reaction of 1-(2-haloaryl)cyclobutanols afforded 3,3-disubstituted α-tetralones. The reaction was applied to the asymmetric synthesis of α-tetralones bearing a chiral quaternary carbon centre at the 3-position, which was otherwise di
