135729-75-8 Usage
Description
PALONOSETRON HCL, also known as Aloxi, is a selective 5-HT3 receptor antagonist that belongs to the class of antiemetic drugs. It is an off-white solid with potent antiemetic properties, making it a valuable pharmaceutical compound for managing nausea and vomiting associated with various medical conditions.
Uses
Used in Pharmaceutical Industry:
PALONOSETRON HCL is used as an antiemetic agent for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It works by blocking the action of serotonin, a neurotransmitter that can cause nausea and vomiting when released in large amounts during chemotherapy. By inhibiting the 5-HT3 receptors, PALONOSETRON HCL effectively reduces the severity and frequency of CINV, improving the quality of life for patients undergoing cancer treatment.
Additionally, PALONOSETRON HCL may also be used in the management of postoperative nausea and vomiting (PONV) and radiotherapy-induced nausea and vomiting (RINV), further demonstrating its versatility as an antiemetic agent in various medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 135729-75-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,7,2 and 9 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 135729-75:
(8*1)+(7*3)+(6*5)+(5*7)+(4*2)+(3*9)+(2*7)+(1*5)=148
148 % 10 = 8
So 135729-75-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H24N2O/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20/h2,4,6,13,15,17H,1,3,5,7-12H2/t15-,17+/m1/s1