1357350-73-2

Basic information

• Product Name: 5-amino-1-(4-chlorophenyl)-1H-pyrimidine-2,4-dione
• Synonyms: 5-amino-1-(4-chlorophenyl)-1H-pyrimidine-2,4-dione
• CAS NO: 1357350-73-2
• Molecular Weight: 237.645
• Mol File: 1357350-73-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-amino-1-(4-chlorophenyl)-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-1-(4-chlorophenyl)-1H-pyrimidine-2,4-dione(1357350-73-2)
• EPA Substance Registry System: 5-amino-1-(4-chlorophenyl)-1H-pyrimidine-2,4-dione(1357350-73-2)

Safety Data

• Hazardous Substances Data: 1357350-73-2(Hazardous Substances Data)

Upstream product

• 101080-71-1 1-(4-chlorophenyl)pyrimidine-2,4(1H,3H)-dione 

Downstream Products

• 1357350-05-0 5-amino-1-(4-chlorophenyl)-3-ethyl-1H-pyrimidine-2,4-dione 
• 1357351-08-6 1-(4-chlorophenyl)-3-ethyl-5-(3-nitrophenylamino)-1H-pyrimidine-2,4-dione 
• 1358965-56-6 1-(4-chlorophenyl)-5-(3-chlorophenylamino)-3-ethyl-1H-pyrimidine-2,4-dione 

Relevant articles and documents

Synthesis and evaluation as PDE4 inhibitors of pyrimidine-2,4-dione derivatives

A series of nitraquazone analogs with a pyrimidindione core was synthesized and tested for inhibitory activity on PDE4, selectivity versus PDE3 and PDE5 and for affinity towards the rolipram high-affinity binding site (HARBS). The 5-anilino derivatives 13