135738-79-3Relevant academic research and scientific papers
PHOSPHORUS ANALOGUES OF AMINO ACIDS AND PEPTIDES XII. REACTION OF SODIUM DIETHYL PHOSPHITE WITH AROMATIC ALDAZINES AND HYDRAZONES
Topolski, M.,Rachon, J.
, p. 97 - 110 (2007/10/02)
The mechanism of the reaction of sodium diethyl phosphite with aromatic aldazines has been investigated.The initially formed monoaddition product (4) reacts with the excess of phosphorus reagent prior to the conceivable addition of diethyl phosphite to the C=N double bond.Cleavage of the N-N single bond is initiated by Single Electron Transfer from phosphite anion to the conjugated N=CH-Ph bond system.The scope of the reaction can be extended to other aromatic hydrazones.There is strong evidence to support the operation of a non-chain SET mechanism.
