1357391-10-6

Basic information

• Product Name: 3(RS)4(RS)-methyl 1-benzyl-2-oxo-4'-phenyl-4'H-spiro[indoline-3,5'-oxazole]-4'-carboxylate
• CAS NO: 1357391-10-6
• Molecular Weight: 412.445
• Mol File: 1357391-10-6.mol

Chemical Properties

• CAS DataBase Reference: 3(RS)4(RS)-methyl 1-benzyl-2-oxo-4'-phenyl-4'H-spiro[indoline-3,5'-oxazole]-4'-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 3(RS)4(RS)-methyl 1-benzyl-2-oxo-4'-phenyl-4'H-spiro[indoline-3,5'-oxazole]-4'-carboxylate(1357391-10-6)
• EPA Substance Registry System: 3(RS)4(RS)-methyl 1-benzyl-2-oxo-4'-phenyl-4'H-spiro[indoline-3,5'-oxazole]-4'-carboxylate(1357391-10-6)

Safety Data

• Hazardous Substances Data: 1357391-10-6(Hazardous Substances Data)

Upstream product

• 1217-89-6 1-benzylisatin 
• 30698-30-7 methyl 2-cyano-2-phenylacetate 

Relevant articles and documents

Cinchona alkaloid-derived thiourea-catalyzed diastereo- and enantioselective [3+2] cycloaddition reaction of isocyanoacetates to isatins: A facile access to optically active spirooxindole oxazolines

An efficient diastereo- and enantioselective [3+2] cycloaddition reaction of α-aryl isocyanoacetates to isatins catalyzed by a quinine-derived bifunctional amine-thiourea-bearing sulfonamide as multiple hydrogen-bonding donor catalyst has been investigated. The corresponding adducts, which bear a spirocyclic quaternary stereocenter at the C-3 position of the oxindole, were obtained in good yields (51-95%), high diastereoselectivities (up to >20:1 dr) and good to excellent enantioselectivities (up to 97% ee). Copyright