1357398-59-4

Basic information

• Product Name: 1-Methyl-2-(2-diphenylphosphinophenyl)-1H-benzoimidazole
• Synonyms: 1-Methyl-2-(2-diphenylphosphinophenyl)-1H-benzoimidazole
• CAS NO: 1357398-59-4
• Molecular Formula: C₂₆H₂₁N₂P
• Molecular Weight: 392.432101
• Mol File: 1357398-59-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 166-172°C
• Appearance: /
• Storage Temp.: 20-25°C
• CAS DataBase Reference: 1-Methyl-2-(2-diphenylphosphinophenyl)-1H-benzoimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-2-(2-diphenylphosphinophenyl)-1H-benzoimidazole(1357398-59-4)
• EPA Substance Registry System: 1-Methyl-2-(2-diphenylphosphinophenyl)-1H-benzoimidazole(1357398-59-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 1357398-59-4(Hazardous Substances Data)

Upstream product

• 88-65-3 2-bromobenzoic-acid 
• 95-54-5 1,2-diamino-benzene 
• 1079-66-9 chloro-diphenylphosphine 
• 92152-36-8 2-(2-bromophenyl)-1-methyl-1H-benzo[d]imidazole 
• 13275-42-8 2-(2-bromophenyl)-benzimidazole 

Relevant articles and documents

Decarboxylative cross-coupling of mesylates catalyzed by copper/palladium systems with customized imidazolyl phosphine ligands

The activation of the inert C-O bonds in mesylates through the use of a new class of imidazolyl phosphines allows the decarboxylative coupling of aryl mesylates as well as polysubstituted alkenyl mesylates. Variation of the ligands leads to two complementary methods providing the corresponding biaryls and polysubstituted olefins in good yields. Copyright

Buchwald-Hartwig amination of aryl chlorides catalyzed by easily accessible benzimidazolyl phosphine-Pd complexes

This study describes the efficacy of benzimidazolyl phosphine ligands, which are easily synthesized from inexpensive and commercially available o-phenylenediamine, 2-bormobenzoic acid, and chlorophosphines, in the Buchwald-Hartwig amination of aryl chlorides. Primary and secondary aromatic/aliphatic amines are effective substrates in this catalytic system. Functional groups such as keto and esters are also compatible. The catalyst loading can be reduced to 0.1 mol% Pd. Georg Thieme Verlag Stuttgart · New York.