13574-14-6 Usage
Uses
Used in Pharmaceutical Formulation:
N,N,N~2~,N~2~-tetramethylglycinamide is used as a co-solvent in the formulation of electrolytes for its ability to improve the solubility of poorly water-soluble drugs, thereby enhancing their bioavailability and effectiveness.
Used in Drug Solubilization:
In the pharmaceutical industry, N,N,N~2~,N~2~-tetramethylglycinamide is utilized as a solubilizing agent to increase the solubility of drugs with poor water solubility, facilitating their formulation and administration.
Used in Protein and Peptide Stabilization:
N,N,N~2~,N~2~-tetramethylglycinamide is employed as a stabilizing agent for proteins and peptides, leveraging its chaotropic properties to maintain their structure and functionality in various applications.
Used in Chemical Reactions:
In the chemical industry, N,N,N~2~,N~2~-tetramethylglycinamide is used as a catalyst or stabilizing agent in a range of chemical reactions, contributing to the efficiency and yield of these processes.
Used in Pharmaceutical Synthesis:
N,N,N~2~,N~2~-tetramethylglycinamide is applied in the synthesis of pharmaceuticals, where its unique properties aid in the production of various medicinal compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 13574-14-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,7 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 13574-14:
(7*1)+(6*3)+(5*5)+(4*7)+(3*4)+(2*1)+(1*4)=96
96 % 10 = 6
So 13574-14-6 is a valid CAS Registry Number.
13574-14-6Relevant academic research and scientific papers
Amines and ammonium compounds. CXCI. The Stevens rearrangement with the participation of the N,N-dimethylcarbamoylmethyl group
Kocharyan, S. T.,Voskanyan, V. S.,Razina, T. L.,Babayan, A. T.
, p. 1721 - 1724 (2007/10/02)
Under the influence of powdered potassium hydroxide in benzene ammonium salts containing a group of the allyl or propargyl type in addition to an N,N-dimethylcarbamoylmethyl group enter smoothly into a Stevens 3,2-rearrangement with the formation of the N,N-dimethylamides of 2-dimethylamino-4-pentenoic and 2-dimethylamino-3,4-pentadienoic acids respectively.The salt, which contains a benzyl group as migrating group, forms a mixture of products from the Stevens and Sommelet rearrangements.The possibility of rearrangement under the influence of sodium in DMSO was demonstrated.
