135741-06-9

Basic information

• Product Name: methyl 3-<(benzyloxycarbonyl)amino>-2-(methoxycarbonyl)-5-oxo-5-(p-chlorophenyl)pentanoate
• CAS NO: 135741-06-9
• Molecular Weight: 447.872
• Mol File: 135741-06-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-<(benzyloxycarbonyl)amino>-2-(methoxycarbonyl)-5-oxo-5-(p-chlorophenyl)pentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-<(benzyloxycarbonyl)amino>-2-(methoxycarbonyl)-5-oxo-5-(p-chlorophenyl)pentanoate(135741-06-9)
• EPA Substance Registry System: methyl 3-<(benzyloxycarbonyl)amino>-2-(methoxycarbonyl)-5-oxo-5-(p-chlorophenyl)pentanoate(135741-06-9)

Safety Data

• Hazardous Substances Data: 135741-06-9(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 84713-20-2 benzyl N-vinylcarbamate 
• 18424-76-5 dimethyl malonate sodium salt 
• 14064-15-4 (4-chlorophenyl)trimethylstannane 

Relevant articles and documents

Palladium(II)-Assisted Dialkylation and Alkylation/Acylation of Optically Active Ene Carbamates via Trialkylorganostannane Cross-Coupling and Carbonylative Coupling Processes

Alkylation of benzyl vinyl carbamate and propene with the anions of diethyl methylmalonate or dimethyl malonate in the presence of palladium(II) chloride, followed by cross-coupling or carbonylative cross-coupling with organostannanes, effected an overall dialkylation or alkylation/acylation of the monoolefin substrate.Complete control of stereochemistry in this palladium(II)-assisted reaction was observed using optically active ene carbamates affording β-amino-unsaturated keto esters in good chemical yields and excellent optical purity.