1357481-05-0Relevant academic research and scientific papers
Enantioselective diels-alder reactions with anomalous endo/exo selectivities using conformationally flexible chiral supramolecular catalysts
Hatano, Manabu,Mizuno, Tomokazu,Izumiseki, Atsuto,Usami, Ryota,Asai, Takafumi,Akakura, Matsujiro,Ishihara, Kazuaki
, p. 12189 - 12192 (2011)
Swapped selectivities: The use of tailor-made catalysts results in anomalous endo/exo selectivities and high enantioselectivities in the Diels-Alder reactions of cyclopentadiene with different acroleins (see scheme). These supramolecular catalysts are prepared in situ from chiral diols, arylboronic acid, and tris(pentafluorophenyl)borane, and can discriminate the re/si face of the dienophile as well as the endo/exo approach of the diene.
