1357481-49-2

Upstream product

• 1357481-50-5 3-pivaloylpyridine N-oxide 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 1357481-45-8 3-(tert-butyl)-1-(4-methylphenylsulfonyl)-1H-pyrazolo[3,4-b]pyridine 
• 1357481-46-9 3-(tert-butyl)-1-(4-methylphenylsulfonyl)-1H-pyrazolo[4,3-c]pyridine 

Relevant academic research and scientific papers

Construction of pyrazolo[3,4-b]pyridines and pyrazolo[4,3-c]pyridines by ring closure of 3-acylpyridine N-oxide tosylhydrazones

3-Acylpyridine N-oxide tosylhydrazones give good overall yields of a mixture of pyrazolo[3,4-b]pyridines and pyrazolo[4,3-c]pyridines when treated with an electrophilic additive and an amine base. (Z)-Hydrazones cyclize readily, while (E)-hydrazones fail