1357587-94-0

Basic information

• Product Name: N-{3-[4-(2-tert-butylaminopyridin-4-yl)-1-(2-fluoroethyl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide
• Synonyms: N-{3-[4-(2-tert-butylaminopyridin-4-yl)-1-(2-fluoroethyl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide
• CAS NO: 1357587-94-0
• Molecular Weight: 591.63
• Mol File: 1357587-94-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{3-[4-(2-tert-butylaminopyridin-4-yl)-1-(2-fluoroethyl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{3-[4-(2-tert-butylaminopyridin-4-yl)-1-(2-fluoroethyl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide(1357587-94-0)
• EPA Substance Registry System: N-{3-[4-(2-tert-butylaminopyridin-4-yl)-1-(2-fluoroethyl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide(1357587-94-0)

Safety Data

• Hazardous Substances Data: 1357587-94-0(Hazardous Substances Data)

Upstream product

• 1357587-92-8 N-{3-[4-(2-tert-butylaminopyridin-4-yl)-1-(tetrahydropyran-2-yl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide 
• 1357587-91-7 2,5-difluoro-N-{2-fluoro-3-[4-(1-oxypyridin-4-yl)-1-(tetrahydropyran-2-yl)-1H-pyrazol-3-yl]phenyl}-N-methoxymethylbenzenesulfonamide 
• 1357587-80-4 N-{3-[4-bromo-1-(tetrahydropyran-2-yl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide 
• 762-51-6 1-fluoro-2-iodoethane 
• 1357587-93-9 N-{3-[4-(2-tert-butylaminopyridin-4-yl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluoro-N-methoxymethylbenzenesulfonamide 

Downstream Products

• 1357586-98-1 N-{3-[4-(2-aminopyridin-4-yl)-1-(2-fluoroethyl)-1H-pyrazol-3-yl]-2-fluorophenyl}-2,5-difluorobenzenesulfonamide 

Relevant articles and documents

DERIVATIVES OF PYRAZOLOPHENYL-BENZENESULFONAMIDE COMPOUNDS AND USE THEREOF AS ANTITUMOR AGENTS

Substituted pyrazolophenyl-benzenesulfonamide compounds of formula (I) are described, wherein m, R1, R2, R3, and R4 are defined in the description, which modulate the activity of protein kinases, These compounds find utility in treating diseases caused by deregulated protein kinase activity, such as cancer and cell proliferative disorders.