135779-82-7Relevant academic research and scientific papers
Derivatives of 1,2-dihydro 2-oxo quinoxalines, their preparation and their use in therapy
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, (2008/06/13)
New derivatives of 1,2-dihydro 2-oxo quinoxalines corresponding to the general formula I: STR1 in which: R is a hydrogen or halogen atom R1 is a hydrogen atom or a straight or branched C1 -C4 alkyl radical R2 is: a hydrogen atom a C(O)R4 radical in which R4 is a straight or branched C1 -C4 alkyl group a C(O)NHR5 radical in which R5 is a straight or branched C1 -C4 alkyl radical or a phenyl group A is a C1 -C4 alkaline chain R3 represents: a hydrogen atom, a C1 -C4 alkyl radical, a C3 -C6 cycloalkyl radical, an alcynyl, nitrile, hydroxyl, carboxamido, pyridyl, phenyl group, or a phenyl group substituted by a halogen atom, a C1 -C4 alkyl group, a C1 -C4 alkoxy group or a nitro group an alkenyl radical of the formula: STR2 in which R6, R7 may, independently of each other, be a hydrogen atom, a C1 -C4 alkyl group, a phenyl group or an alkoxycarbonyl group a radical of the formula: in which R8 represents a C1 -C4 alkyl radical a radical of the formula: in which R9 represents a straight or branched C1 -C4 alkyl group, or a phenyl group may assume values from 2 to 4. as well as the therapeutically acceptable organic or inorganic salts of these molecules. The compounds are useful in the treatment of respiratory disorders.
