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Farnesylthioacetic Acid (FTA), also known as S-Farnesyl thioacetic acid, is an analog of S-farnesyl cysteine that functions as a competitive inhibitor of isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). This molecule has the ability to inhibit the methylation of both farnesylated and geranylgeranylated substrates, making it a significant compound in the field of biochemistry and pharmaceuticals.

135784-48-4

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135784-48-4 Usage

Uses

Used in Pharmaceutical Industry:
Farnesylthioacetic Acid is used as a research compound for its ability to inhibit isoprenylated protein methyltransferase. This inhibition can be crucial in studying the role of protein methylation in various cellular processes and its potential implications in disease development.
Used in Cancer Research:
Farnesylthioacetic Acid is used as a potential therapeutic agent in cancer research. By inhibiting the methylation of farnesylated and geranylgeranylated substrates, FTA can potentially disrupt the signaling pathways involved in cancer cell growth and proliferation, making it a valuable tool in the development of novel cancer treatments.
Used in Drug Development:
Farnesylthioacetic Acid is used as a lead compound in the development of new drugs targeting protein methylation. Its ability to inhibit specific methylation processes can be leveraged to create targeted therapies for various diseases, including cancer and other conditions related to abnormal protein methylation.

Check Digit Verification of cas no

The CAS Registry Mumber 135784-48-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,7,8 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 135784-48:
(8*1)+(7*3)+(6*5)+(5*7)+(4*8)+(3*4)+(2*4)+(1*8)=154
154 % 10 = 4
So 135784-48-4 is a valid CAS Registry Number.

135784-48-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name FARNESYLTHIOACETIC ACID

1.2 Other means of identification

Product number -
Other names FTA

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:135784-48-4 SDS

135784-48-4Upstream product

135784-48-4Downstream Products

135784-48-4Relevant academic research and scientific papers

COMPOUNDS AND METHODS FOR USE IN TREATING NEOPLASIA AND CANCER

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Page/Page column 72; 93; 94, (2013/03/26)

The present invention relates to a novel method for the treatment of neoplasia, including cancer and other diseases and conditions in humans and mammals. More particularly, in preferred aspects, the present invention provides a method for the use of novel compounds for the treatment of neoplasia, hyperproliferative cell growth including psoriasis, restenosis following cardiovascular surgery, hyperplasia, including renal hyperplasia, chronic inflammatory diseases including rheumatoid and osteoarthritis, among others.

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