135792-57-3Relevant academic research and scientific papers
REGIOSELECTIVE ENZYME-MEDIATED ACYLATION OF COLCHICOSIDE AND THIOCOLCHICOSIDE
Danieli, Bruno,Bellis, Paolo De,Carrea, Giacomo,Riva, Sergio
, p. 123 - 125 (2007/10/02)
The natural alkaloid colchicoside, 1 and its sulphur synthetic analogue thiocolchicoside, 3, have been enzymatically acylated by the protease subtilisin in anhydrous pyridine.High degrees of conversion with excellent regioselectivity for the primary OH of
