1357932-85-4Relevant academic research and scientific papers
An efficient and practical synthesis of aryl and hetaryl α-keto esters
Raghunadh, Akula,Meruva, Suresh Babu,Kumar, Nuka Anil,Kumar, Gudla Santosh,Rao, L. Vaikunta,Syamkumar
, p. 283 - 289 (2012)
A general and highly efficient method was developed for the synthesis of -keto esters by oxidative esterification of 2,2-dibromo-1-(het)arylethanones by sequential treatment with dimethyl sulfoxide and an alkanol. The versatility of the reaction was established by synthesizing a range of -keto esters by treatment of 2,2-dibromoethanones, derived from aryl or hetaryl ketones, with di-methyl sulfoxide and a cyclic or acyclic primary or secondary alcohol. The mechanism of the reaction was established by means of a detailed study. Georg Thieme Verlag Stuttgart · New York.
