1357945-38-0

Basic information

• Product Name: 4-b]pyridine
• Synonyms: 3-broMo-4-chloro-1H-pyrazolo[3;3-BroMo-4-chloro-1H-pyrazolo[3,4-b]pyridine
• CAS NO: 1357945-38-0
• Molecular Formula: C6H3BrClN3
• Molecular Weight: 232.46512
• Mol File: 1357945-38-0.mol

Chemical Properties

• Boiling Point: 367.7±37.0 °C(Predicted)
• Appearance: /
• Density: 1.996±0.06 g/cm3(Predicted)
• PKA: 6.56±0.40(Predicted)
• CAS DataBase Reference: 4-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-b]pyridine(1357945-38-0)
• EPA Substance Registry System: 4-b]pyridine(1357945-38-0)

Safety Data

• Hazardous Substances Data: 1357945-38-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry Research:
4-b]pyridine is used as a research compound for studying the behavior of heterocyclic compounds and developing new synthetic methods. Its unusual structure and high reactivity make it a valuable tool in understanding the properties and reactions of similar compounds.
Used in Medicinal Chemistry and Drug Development:
4-b]pyridine may have potential applications in the field of medicinal chemistry and drug development due to its unique structure and reactivity. It could be utilized in the design and synthesis of new pharmaceutical compounds, although further research is needed to fully understand its properties and potential uses in this area.

Upstream product

• 924909-11-5 1H-pyrazolo[3,4-b]pyridine 7-oxide 
• 271-73-8 1H-Pyrazolo[3,4-b]pyridine 
• 29274-28-0 4-Chloro-1H-pyrazolo<3,4-b>pyridine 
• 924909-17-1 4-chloro-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridine 
• 949556-46-1 5-(((1-(4-methoxybenzyl)-1H-pyrazol-5-yl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 924909-16-0 1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-ol 

Relevant articles and documents

INHIBITORS OF BRUTON'S TYROSINE KINASE

Disclosed herein are compounds that inhibit Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. In addition, reversible inhibitors of Btk are also described. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.

SUBSTITUTED 1H-PYRROLO [2,3-B] PYRIDINE AND 1H-PYRAZOLO [3, 4-B] PYRIDINE DERIVATIVES AS SALT INDUCIBLE KINASE 2 (SIK2) INHIBITORS

The present invention relates to compounds according to Formulas I, IA or IB: to pharmaceutically acceptable composition, salts thereof, their synthesis and their use as SIK2 inhibitors including such compounds and methods of using said compounds in the treatment of various diseases and or disorders such as cancer, stroke, cardiovascular, obesity and type II diabetes.