135795-90-3

Usage

Uses

Used in Scientific Research:
DL-MBDB:HCL is used as a research chemical for studying the effects and mechanisms of action of entactogens and psychoactive substances. It helps researchers understand the interactions between these compounds and the human brain, as well as their potential therapeutic applications.
Used in Recreational Settings:

InChI:InChI=1/C12H17NO2/c1-3-4-11(13-2)9-5-6-10-8-14-15-12(10)7-9/h5-7,11,13H,3-4,8H2,1-2H3

Upstream product

• 593-51-1 methylamine hydrochloride 
• 23023-13-4 1-(1,3-benzodioxol-5-yl)butan-2-one 
• 16929-04-7 (E)-5-(but-1-en-1-yl)benzo[d][1,3]dioxole 
• 120-57-0 piperonal 
• 6890-31-9 1-(1,3-benzodioxol-5-yl)butan-1-ol 

Relevant academic research and scientific papers

Derivatives of 1-(1,3-benzodioxol-5-yl)-2-butanamine: Representatives of a novel therapeutic class

The α-ethyl phenethylamine derivative 1-(1,3-benzodioxol-5-yl)-2-butanamine was prepared. An asymmetric synthesis was used to prepare the enantiomers of this compound and the related α-methyl homologue (MDA). The racemates and enantiomers of both compounds were evaluated in the two-lever drug discrimination assay in rats trained to discriminate saline from 0.08 mg/kg of LSD tartrate. Stimulus generalization occurred with the racemate and the R-(-)enantiomer of the α-methyl homologue and the S-(+)enantiomer of the α-ethyl primary amine. No generalization occurred with the other enantiomers or with the N-methyl derivatives of either series. Human psychopharmacology studies revealed that the N-methyl derivative of the title compound was nonhallucinogenic and that it had a new, novel psychoactive effect. It is suggested that this compound is the prototype of a new pharmacologic class that may have value in facilitating psychotherapy and that this class be designated as entactogens.