135799-48-3Relevant academic research and scientific papers
Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential
Appendino, Giovanni,De Petrocellis, Luciano,Trevisani, Marcello,Minassi, Alberto,Daddario, Nives,Moriello, Aniello Schiano,Gazzieri, David,Ligresti, Alessia,Campi, Barbara,Fontana, Gabriele,Pinna, Christian,Geppetti, Pierangeio,Di Marzo, Vincenzo
, p. 561 - 570 (2007/10/03)
Olvanil (N-9-Z-octadecenoyl-vanillamide) is an agonist of transient receptor potential vanilloid type 1 (TRPV1) channels that lack the pungency of capsaicin and was developed as an oral analgesic. Vanillamides are unmatched in terms of structural simplici
Cleavage of Esters under Nearly Neutral Conditions at High Pressure. Chemo- and Regioselective Hydrolysis in Organic Solvents
Yamamoto, Yoshinori,Furuta, Toshiaki,Matsuo, Jiro,Kurata, Tetsuro
, p. 5737 - 5738 (2007/10/02)
Hydrolysis of esters proceeded at room temperature under high pressure in the presence of iPr2NEt or N-methylmorpholine using CH3CN-H2O (60:1) as the solvent.This very mild procedure enables the smooth hydrolysis of biologically important compounds such as amino esters, aliphatic unsaturated fatty esters, and β-hydroxy esters; no racemization, no isomerization, and no side reactions take place.
