135810-41-2

Usage

Chemical class

Dibenzo[b,f][1,4]oxazepine derivatives

Structure

Cyclic amide with two benzene rings fused to an oxazepine ring

Substituent

10-propyl group attached to position 10

Functional group

Amide (-CONH-) present in the structure

Potential applications

Organic chemistry, pharmaceuticals, and material science

Reactivity

Unique structure and potential reactivity for further research

Further study

Research and study needed to understand properties and uses

Molecular weight

Approximately 307.39 g/mol (calculated from the molecular formula)

Stereochemistry

The presence of a chiral center at the propyl group may lead to enantiomers or diastereomers, depending on the substitution pattern.

Upstream product

• 3158-85-8 10H-dibenzo[b,f][1,4]oxazepin-11-one 
• 106-94-5 propyl bromide 
• 95-56-7 2-hydroxybromobenzene 
• 346695-08-7 2-bromo-N-propylbenzamide 

Downstream Products

• 135810-43-4 10-propyl-10H-dibenz[b,f][1,4]oxazepin-11-thione 

Relevant academic research and scientific papers

Ligand-Controlled Chemoselective One-Pot Synthesis of Dibenzothiazepinones and Dibenzoxazepinones via Twice Copper-Catalyzed Cross-Coupling

A highly efficient and generally applicable protocol, starting from 2-bromobenzamides and 2-bromo(thio)phenols via twice copper-catalyzed couplings to afford dibenzothiazepines and dibenzoxazepinones has been developed. High levels of yield and chemoselectivity are achieved in a single-pot reaction by using an appropriate ligand. Moreover, this facile methodology allows rapid access to a variety of bio-active compounds and known psychotropic drug, which should broaden its application in organic synthesis.

Dibenz[b,f][1,4]oxazepin(and thiazepin)-11(10H)-ones and-thiones and their use in the prevention or treatment of HIV infection

Disclosed is the use of dibenz[b,f][1,4]oxazepin (or thiazepin)-11(10H)-ones and -thiones in the prevention and treatment of AIDS, ARC and related disorders associated with HIV infection.