135869-28-2Relevant academic research and scientific papers
2-naphthylcarbapenems: Broad spectrum antibiotics with enhanced potency against MRSA
Greenlee, Mark L.,DiNinno, Frank,Herrmann, Jeffrey J.,Jaworsky, Cynthia,Muthard, David A.,Salzmann, Thomas N.
, p. 2893 - 2896 (2007/10/03)
A regioisomeric set of 2-naphthylcarbapenems featuring cationic substituents was synthesized. Optimal placement of the cationic group was found to markedly improve activity against methicillin-resistant staphylococci while maintaining a good spectrum of gram-negative activity.
