1358693-98-7Relevant academic research and scientific papers
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: Structure-based design, synthesis, and biological evaluation
Chiriano, Gianpaolo,De Simone, Angela,Mancini, Francesca,Perez, Daniel I.,Cavalli, Andrea,Bolognesi, Maria Laura,Legname, Giuseppe,Martinez, Ana,Andrisano, Vincenza,Carloni, Paolo,Roberti, Marinella
, p. 206 - 213 (2012/03/26)
In this work, we report a rational structure-based approach aimed at the discovery of new 2-aminoimidazoles as β-secretase inhibitors. Taking advantage of a microwave-assisted synthetic protocol, a small library of derivatives was obtained and biologicall
