1358796-52-7Relevant academic research and scientific papers
Nitrone ylides: Two possible 1,3-dipolar cycloadditions but only one stepwise formation of all-cis-5-aryl-2,3,5-trisubstituted N-hydroxypyrrolidines
Merino, Pedro,Tejero, Tomas,Diez-Martinez, Alba,Gueltekin, Zeynep
supporting information; experimental part, p. 6567 - 6573 (2011/12/15)
An efficient methodology for the synthesis of all-cis-N-hydroxypyrrolidines has been developed through the formal [3+2] dipolar cycloaddition of electron-poor alkenes and nitrone ylides generated from N- (methoxycarbonylmethyl)nitrones. Treatment of the n
