135883-16-8 Usage
General Description
(3aR,12bR)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepin[4,5-c]pyrrole maleate is a chemical compound with the molecular formula C20H19ClNO4. It is a maleate salt of a pyrrole derivative and is commonly used as a pharmaceutical intermediate. (3aR,12bR)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepin[4,5-c]pyrrole maleate has been studied for its potential medicinal properties, including its impact on the central nervous system and potential use as an antidepressant and antipsychotic. It has also been explored for its potential in treating chronic pain conditions. Additionally, studies have shown that this molecule has significant binding affinity for certain serotonin and dopamine receptors, suggesting potential applications in the treatment of neurological disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 135883-16-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,8,8 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 135883-16:
(8*1)+(7*3)+(6*5)+(5*8)+(4*8)+(3*3)+(2*1)+(1*6)=148
148 % 10 = 8
So 135883-16-8 is a valid CAS Registry Number.
135883-16-8Relevant articles and documents
A method for the preparation of asenapine
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Paragraph 0025-0027, (2017/02/09)
The invention relates to a preparation method of a psychotropic medicine asenapine. The method comprises a step that asenapine is prepared through a reaction of a raw material trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-monobenzo[2,3:6,7]oxepino[4,5-C]pyrrole-1-one or trans-11-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenzo[2,3:6,7]oxepino[4,5-C]pyrrole-1-one under the action of a reducing agent sodium bisaluminumhydride or a composite reducing agent composed of sodium bisaluminumhydride and other regents. The method has the advantages of mild and controllable reaction technology, low production cost, good product yield, realization of the large scale application in the industrial production, and good enforcement values and social and economic benefits.
