135895-61-3Relevant academic research and scientific papers
An alternative regioselective ring-opening of epoxides to chlorohydrins mediated by chlorotitanium(IV) reagents
Nishitani, Kiyoshi,Shinyama, Kyoko,Yamakawa, Koji
, p. 191 - 197 (2008/09/17)
A regioselective cleavage of various epoxides to vic-chlorohydrin isomers by using TiCl4 or TiCl4-Ti(O-i-Pr)4 complex was investigated. The less substituted alcohols, C2-attack products, were formed by the use of TiCl4 in CH2Cl2. On the other hand, the less substituted chlorides, Cl-attack products, were formed by using TiCI(O-i-Pr)3 in DMF. These regioselectivities depend on both the acidity of the Lewis acids and the polarity of the solvents.
Reductive ring-opening reaction of 2,3-epoxy-1,4-butanediones with SbCl3-Bu4NI in the presence of Na2S 2O3·5H2O
Sayama, Shinsei
, p. 2115 - 2124 (2007/10/03)
1,4-Disubstituted 2,3-epoxy-1,4-butanediones were converted to 1,4-disubstituted 2-hydroxy-1,4-butanediones with SbCl3-Bu 4NI in the presence of Na2S2O 3-5H2O. The ring opening of terminal epoxides can also be accomplished to afford the corresponding haloalcohol with SbCl3 and tetrabutylammonium halides, Bu4NX (X = Cl, Br, I) under the same reaction conditions. Copyright Taylor & Francis, Inc.
In vivo studies on the metabolism of the monoterpenes S-(+)- and R-(-)-carvone in humans using the metabolism of ingestion-correlated amounts (MICA) approach
Engel
, p. 4069 - 4075 (2007/10/03)
The major in vivo metabolites of S-(+)- and R-(-)-carvone in a metabolism of ingestion correlated amounts (MICA) experiment were newly identified as α,4-dimethyl-5-oxo-3-cyclohexene-1-acetic acid (dihydrocarvonic acid), α-methylene-4-methyl-5-oxo-3-cycloh
Chemo and regioselective opening of ethereal carbon-oxygen bonds by monochloroborane-dimethylsulfide
Bovicelli, Paolo,Mincione, Enrico,Ortaggi, Giancarlo
, p. 3719 - 3722 (2007/10/02)
Monochloroborane-dimethylsulfide 1 is a mild chemo and regioselective reagent useful in the opening of epoxides, THP ethers, ketals and ethers.
