135895-62-4Relevant academic research and scientific papers
An alternative regioselective ring-opening of epoxides to chlorohydrins mediated by chlorotitanium(IV) reagents
Nishitani, Kiyoshi,Shinyama, Kyoko,Yamakawa, Koji
, p. 191 - 197 (2008/09/17)
A regioselective cleavage of various epoxides to vic-chlorohydrin isomers by using TiCl4 or TiCl4-Ti(O-i-Pr)4 complex was investigated. The less substituted alcohols, C2-attack products, were formed by the use of TiCl4 in CH2Cl2. On the other hand, the less substituted chlorides, Cl-attack products, were formed by using TiCI(O-i-Pr)3 in DMF. These regioselectivities depend on both the acidity of the Lewis acids and the polarity of the solvents.
Chemo and regioselective opening of ethereal carbon-oxygen bonds by monochloroborane-dimethylsulfide
Bovicelli, Paolo,Mincione, Enrico,Ortaggi, Giancarlo
, p. 3719 - 3722 (2007/10/02)
Monochloroborane-dimethylsulfide 1 is a mild chemo and regioselective reagent useful in the opening of epoxides, THP ethers, ketals and ethers.
