135962-83-3Relevant academic research and scientific papers
Partial Kinetic 'Resolution' Resulting from a Deuterium Isotope Effect
Anastasis, Panayiotis,Duffin, Raymond,Gilmore, Christopher,Overton, Karl
, p. 801 - 802 (1991)
The 'racemate' 1A/1B cyclises on heating to the enol 5 via an 'ene' reaction; at two-thirds completion, the recovered enone 1A/1B has D -62 deg (1B has D -132 deg); kinetic 'resolution' results from a deuterium isotope effect for the cyclization (kH/kD ca. 1.8); the absolute stereochemistry of compound 6a is determined by X-ray analysis.
