135967-20-3

Upstream product

• 126-81-8 dimedone 
• 41736-99-6 (+/-)-3,3-dimethylhexane-1,5-diol 
• 78-59-1 3,5,5-Trimethylcyclohex-2-en-1-one 
• 13865-50-4 methoxymethyl phenyl sulfide 
• 135967-19-0 6-(tert-Butyl-diphenyl-silanyloxy)-4,4-dimethyl-hexan-2-one 

Downstream Products

• 135967-23-6 (2R,3R)-7-(tert-Butyl-diphenyl-silanyloxy)-3,5,5-trimethyl-3-phenylsulfanyl-heptan-2-ol 
• 135967-23-6 (2S,3R)-7-(tert-Butyl-diphenyl-silanyloxy)-3,5,5-trimethyl-3-phenylsulfanyl-heptan-2-ol 
• 135967-25-8 (5R,6R)-3,3,5-Trimethyl-5-phenylsulfanyl-heptane-1,6-diol 
• 135967-25-8 (5R,6S)-3,3,5-Trimethyl-5-phenylsulfanyl-heptane-1,6-diol 
• 135967-27-0 (R)-2,4,4-Trimethyl-2-((R)-1-phenylsulfanyl-ethyl)-tetrahydro-pyran 
• 135967-27-0 (R)-2,4,4-Trimethyl-2-((S)-1-phenylsulfanyl-ethyl)-tetrahydro-pyran 
• 135967-21-4 2,4,4-Trimethyl-2-phenylsulfanyl-hexane-1,6-diol 
• 135967-22-5 2,4,4-Trimethyl-2-phenylsulfanylmethyl-tetrahydro-pyran 

Relevant academic research and scientific papers

Synthesis of tetrahydropyrans by hydroxyl participation in phenylthio migration

Acid-catalysed cyclisation of substituted 1,6- or 1,4-alkane diols with suitably placed phenylthio groups leads to high yields of tetrahydropyrans formed by exo or endo hydroxyl participation during phenylthio migration with inversion at both the migration origin and terminus.