135983-07-2

Basic information

• Product Name: C₁₂H₁₇NO₂S
• Synonyms: C₁₂H₁₇NO₂S
• CAS NO: 135983-07-2
• Molecular Weight: 239.338
• Mol File: 135983-07-2.mol

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₇NO₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₇NO₂S(135983-07-2)
• EPA Substance Registry System: C₁₂H₁₇NO₂S(135983-07-2)

Safety Data

• Hazardous Substances Data: 135983-07-2(Hazardous Substances Data)

Upstream product

• 1073-72-9 4-hydroxythioanisole 
• 88-10-8 N,N-diethylcarbamyl chloride 

Downstream Products

• 1646629-90-4 N,N-diethyl-2-hydroxy-5-(methylthio)benzamide 

Relevant articles and documents

C-O Bond Silylation Catalyzed by Iron: A General Method for the Construction of Csp2-Si Bonds

The iron-catalyzed construction of Csp2-Si bonds via unreactive C-O bonds possesses a challenging topic in organic chemistry. Herein we report an iron-catalyzed silylation of aryl and alkenyl carbamates via C-O bond activation. This protocol fe

Lithiation of a silyl ether: Formation of an ortho-fries hydroxyketone

A hydroxy-directed alkylation of an N,N-diethylarylamide using CIPE-assisted α-silyl carbanions (CIPE=complex-induced proximity effect) has been developed using a simple reagent combination of LDA (lithium diisopropylamide) and chlorosilane. A study of the mechanism, and the application of the procedure to an anionic Snieckus-Fries rearrangement for a highly efficient synthesis of the potent phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002, are reported.