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1359873-45-2

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1359873-45-2 Usage

Description

6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine Hydrochloride is a chemical compound with a complex structure, characterized by its potential therapeutic applications in the field of oncology. It is derived from thieno[2,3-d]pyrimidine, a heterocyclic compound, and features a 6-ethyl and 4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl substitution pattern. 6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyriMidine Hydrochloride is of interest due to its ability to interact with specific protein targets, making it a promising candidate for the development of novel therapeutic strategies against certain types of cancer.

Uses

Used in Pharmaceutical Industry:
6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine Hydrochloride is used as an inhibitor of the fusion protein interaction of menin-mixed lineage leukemia (menin-MLL) for the treatment of MLL-associated leukemia. By targeting the menin-MLL interaction, this compound downregulates the expression of target genes required for MLL fusion protein oncogenic activity, effectively reversing MLL fusion protein-mediated leukemic transformation. This makes it a valuable tool in the development of targeted therapies for patients suffering from MLL-related leukemia.
Used in Research and Development:
In the field of drug discovery and development, 6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine Hydrochloride serves as a valuable research tool for understanding the molecular mechanisms underlying MLL fusion protein-mediated leukemogenesis. Its use in various in vitro and in vivo models allows researchers to study the compound's efficacy, safety, and potential side effects, paving the way for the development of more effective and safer treatments for MLL-associated leukemia.
Used in Drug Delivery Systems:
Similar to gallotannin, 6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine Hydrochloride may also benefit from novel drug delivery systems to enhance its applications and efficacy against cancer cells. Various organic and metallic nanoparticles could be employed as carriers for this compound, aiming to improve its delivery, bioavailability, and therapeutic outcomes in the treatment of MLL-associated leukemia.

Check Digit Verification of cas no

The CAS Registry Mumber 1359873-45-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,9,8,7 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1359873-45:
(9*1)+(8*3)+(7*5)+(6*9)+(5*8)+(4*7)+(3*3)+(2*4)+(1*5)=212
212 % 10 = 2
So 1359873-45-2 is a valid CAS Registry Number.

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1359873-45-2Downstream Products

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