1359986-22-3Relevant academic research and scientific papers
Me3(OMe)tBuXPhos: A surrogate ligand for Me4tBuXPhos in palladium-catalyzed C-N and C-O bond-forming reactions
Ueda, Satoshi,Ali, Siraj,Fors, Brett P.,Buchwald, Stephen L.
, p. 2543 - 2547 (2012/05/20)
A new biarylphosphine ligand, Me3(OMe)tBuXPhos (L3), was designed as a surrogate for Me4tBuXPhos (L1). The Me 3(OMe)tBuXPhos could be prepared in a chromatography-free manner from inexpensive and readily available 2,3,6-trimethylphenol. Comparative studies demonstrated that a catalyst based on Me3(OMe)tBuXPhos displayed the same reactivity as a catalyst based on Me4tBuXPhos for Pd-catalyzed C-N and C-O bond-forming processes.
