1360-76-5

Basic information

• Product Name: ranaconitine
• Synonyms: ranaconitine;20-Ethyl-1α,14α,16β-trimethoxyaconitane-4,7,8,9-tetrol 4-[2-(acetylamino)benzoate];4-[2-(Acetylamino)benzoyloxy]-20-ethyl-1α,14α,16β-trimethoxyaconitane-7,8,9-triol;O4-(2-Acetamidobenzoyl)ranaconine;(1alpha,14alpha,16beta)-Aconitane-4,7,8,9-tetrol 20-ethyl-1,14,16-trimethoxy-4-[2-(acetylamino)benzoate];7-Hydroxylappaconitine
• CAS NO: 1360-76-5
• Molecular Formula: C32H44N2O9
• Molecular Weight: 600.705
• Mol File: 1360-76-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 132-134℃
• Boiling Point: 758.9°Cat760mmHg
• Flash Point: 412.8°C
• Appearance: /
• Density: 1.39
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.637
• PKA: 12.08±0.70(Predicted)
• CAS DataBase Reference: ranaconitine(CAS DataBase Reference)
• NIST Chemistry Reference: ranaconitine(1360-76-5)
• EPA Substance Registry System: ranaconitine(1360-76-5)

Safety Data

• Hazardous Substances Data: 1360-76-5(Hazardous Substances Data)

Usage

Description

Ranaconitine is an aconitine alkaloid derived from the ethanolic extract of the Bulgarian plant Aconitum ranunculaefolium. It forms colorless needles when crystallized from ethanol and exhibits dextrorotatory optical activity with a specific rotation of [α]D +33.2° (c 0.5, CHCI3). Upon hydrolysis with 5% KOH, it yields ranaconine (C23H37NO7) with a melting point of 107-109°C and N-acetylanthranilic acid.

Uses

Used in Pharmaceutical Industry:
Ranaconitine is used as a pharmaceutical compound for its potential therapeutic applications. The expression is: Ranaconitine is used as a pharmaceutical compound for its potential therapeutic applications due to its alkaloid properties and interactions with various biological systems.
Used in Research and Development:
Ranaconitine is also used as a research compound for studying its chemical properties, structural characteristics, and potential applications in drug development. The expression is: Ranaconitine is used as a research compound for studying its chemical properties, structural characteristics, and potential applications in drug development, contributing to the advancement of pharmaceutical sciences.
Please note that the provided materials do not explicitly mention specific applications of ranaconitine. The uses listed above are inferred based on its classification as an aconitine alkaloid and its potential relevance in the pharmaceutical and research industries.

InChI:InChI=1/C32H44N2O9/c1-6-34-16-28(43-26(36)18-9-7-8-10-20(18)33-17(2)35)12-11-24(41-4)31-22-13-19-21(40-3)14-30(38,32(22,39)25(19)42-5)29(37,27(31)34)15-23(28)31/h7-10,19,21-25,27,37-39H,6,11-16H2,1-5H3,(H,33,35)/t19-,21+,22+,23-,24+,25+,27?,28-,29-,30+,31-,32+/m1/s1