136005-87-3

Upstream product

• 35784-51-1 ethyl 2,3,4-tri-O-benzoyl-1-thio-β-D-glucopyranoside 
• 75557-23-2 3,4,6-tri-O-acetyl-1,2-O-(1-p-tolylthioethylidene)-α-D-glucopyranose 
• 74808-10-9 O-(2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl)trichloroacetimidate 

Relevant academic research and scientific papers

SYNTHESIS OF TIMOSAPONIN BII

The invention provides a synthetic route from sarsasapogenin to timosaponin BII a related compounds. A diketone intermediate is provided, which can advantageously used for in situ assembly of complex sugar moieties of the desired glycone end product. The

SYNTHESIS OF TIMOSAPONIN BII

The invention provides a synthetic route from sarsasapogenin to timosaponin BII and related compounds.A diketone intermediate is provided, which can advantageously be used for in situ assembly of complex sugar moieties of the desired glycone end product.

Potential usefulness of sugar 1,2 thio ortho esters in iodonium-promoted glycosidation

Sugar 1,2 thio ortho esters can be condensed with terminal glycosyl acceptors using iodonium-ion sources (IDCP and NIS/TfOH) as activators.IDCP- or NIS/TfOH-assisted glycosidation of sugar 1,2 thio ortho esters with primary hydroxyl groups of "armed" or "

IODONIUM ION-PROMOTED GLYCOSIDATION OF SUGAR 1,2-THIO-ORTHOESTERS

Sugar 1,2-thio-orthoesters could be condensed with terminal glycosidic acceptors using halonium ion sources (IDCP, NIS/TfOH, NCS/TfOH) as activators.IDCP or NIS/TfOH-assisted glycosidation of sugar 1,2-thio-orthoesters with disarmed alkyl 1-thioglycosides