1360059-35-3Relevant academic research and scientific papers
Iodine-mediated regioselective C2-amination of indoles and a concise total synthesis of (±)-folicanthine
Li, Ying-Xiu,Wang, Hai-Xi,Ali, Shaukat,Xia, Xiao-Feng,Liang, Yong-Min
supporting information; experimental part, p. 2343 - 2345 (2012/05/04)
Highly substituted 2-aminated indoles can be prepared in moderate to excellent yields by regioselective C2-amination of indoles promoted by iodine. As a key step in a concise synthesis of (±)-folicanthine, its core structure was easily obtained by one step cyclization-dimerization of substituted tryptophan in high yield on a gram scale. The Royal Society of Chemistry.
