136009-46-6Relevant articles and documents
2,3-dihydro-4(1H)-quinazolinone compound as well as medicine composition and application thereof
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Paragraph 0074; 0079; 0080; 0081; 0082; 0083-0085; 0127-0130, (2019/04/11)
The invention relates to a 2,3-dihydro-4(1H)-quinazolinone compound as well as a medicine composition and application thereof. The 2,3-dihydro-4(1H)-quinazolinone compound has the main technical scheme that the structural general formula of the 2,3-dihydro-4(1H)-quinazolinone compound is shown as the formula (I) in the description; R1 is one of the following groups of hydrogen, methyl, methoxyl and halogen; R2 is one of the following groups of phenyl, a first group obtained by substituting at least one hydrogen in the phenyl by a substituent group, a pyridine group, a second group obtained bysubstituting at least one hydrogen in the pyridine group by a substituent group, a thiophene group, a furan group, saturated alicyclic hydrocarbon or first chain hydrocarbon; R3 is one of the following groups of phenyl, a third group obtained by substituting at least one hydrogen in the phenyl by a substituent group, a pyridine group, a thiophene group, a furan group, saturated alicyclic hydrocarbon and second chain hydrocarbon. The quinazolinone compound is mainly designed and synthesized; the compound can be used for preparing TRPC4 inhibitors or agonists, and preparing diabetes treatment medicine.