1360105-45-8

Upstream product

• 1373947-37-5 4-chloro-6-((3-chloro-4-isopropoxyphenyl)amino)-1-(4-chlorobenzyl)-1,3,5-triazin-2(1H)-one 
• 1360105-43-6 ethyl (E)-3-(6-((3-chloro-4-isopropoxyphenyl)amino)-5-(4-chlorobenzyl)-4-oxo-4,5-dihydro-1,3,5-triazin-2-yl)acrylate 

Downstream Products

• 1239685-54-1 3-(6-((3-chloro-4-isopropoxyphenyl)amino)-5-(4-chlorobenzyl)-4-oxo-4,5-dihydro-1,3,5-triazin-2-yl)propanoic acid 

Relevant academic research and scientific papers

NOVEL TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

The present invention provides a novel P2X3 and/or P2X2/3 receptor antago nist. A compound represented by the formula (I): wherein Ra, Rb and Rc are, (a) Ra and Rb are taken together =Z; and Rc is a group represented by R1c; or (b) Rb and Rc are taken together to form a bond; and Ra is a group represented by -Y-R1a; R1a and R1c are each independently hydrogen, substituted or unsubstituted alkyl, etc.; R2 and R3 are each independently substituted or unsubstituted aryl, etc.; R4a and R4b are each independently hydrogen, substituted or unsubstituted alkyl, etc.; X is -N(R5)-, etc.; R5 is hydrogen, substituted or unsubstituted lower alkyl, etc.; -Y- is -O-, etc.; =Z is =O, etc.; and n is an integer of 0 to 4.