1360157-19-2Relevant academic research and scientific papers
Design and synthesis of an Fmoc-SPPS-compatible amino acid building block mimicking the transition state of phosphohistidine phosphatase
Eerland, Martijn F.,Hedberg, Christian
experimental part, p. 2047 - 2052 (2012/04/23)
The synthesis of a sulfonamide-based transition-state (TS) analogue of enzymatic phosphohistidine dephosphorylation as an amino acid building block is presented, together with the proof-of-concept of its incorporation into peptides. Key features include f
