1360181-60-7Relevant academic research and scientific papers
New use of bis(benzotriazolyl)-1,2-(dialkylamino)ethanes for the synthesis of 2-H-3-dialkylamino imidazo[1,2-a]pyrazine derivatives
Pastor, Joaquín,Rodríguez-Arístegui, Sonsoles,Hernández, Ana Isabel,Varela, Carmen,Salgado, Antonio,Martínez, Sonia
, p. 1082 - 1084 (2012/03/26)
First direct synthesis of 2-H-3-N-dialkyl-imidazo[1,2-a]pyrazines is described. This approach makes use of accessible substituted pyrazines and the assistance of benzotriazole. In such a manner we accomplished the introduction of cyclic amines at C-3 of the scaffold in a convenient formal cyclisation procedure. Detailed examples and utility of this approach are presented herein.
