136032-94-5

Basic information

• Product Name: (S)-2-phenylvaline
• CAS NO: 136032-94-5
• Molecular Weight: 193.246
• Mol File: 136032-94-5.mol

Chemical Properties

• CAS DataBase Reference: (S)-2-phenylvaline(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-phenylvaline(136032-94-5)
• EPA Substance Registry System: (S)-2-phenylvaline(136032-94-5)

Safety Data

• Hazardous Substances Data: 136032-94-5(Hazardous Substances Data)

Upstream product

• 136032-90-1 C₁₆H₂₇NO₃ 
• 135998-86-6 (1R,2R,5S,9R)-5-Isopropyl-2,10,10-trimethyl-5-phenyl-3-oxa-6-aza-tricyclo[7.1.1.0^2,7]undec-6-en-4-one 

Relevant articles and documents

Enantioselective Synthesis of α-Quaternary Amino Acids by Alkylation of Deprotonated α-Aminonitriles

A series of α-quaternary arylglycines were prepared in high optical purity (up to 98% ee) by α-alkylation of deprotonated α-aminonitriles derived by the Strecker reaction from (4S,5S)-5-amino-2,2-dimethyl-4-phenyl-1,3-dioxane. The procedure includes only chromatographic purification of the final products and is devoid of chromatography or crystallization operations on intermediates to raise the optical purity.

REACTIONS OF FLUOROBENZENE TRICARBONYLCHROMIUM COMPLEXES WITH ANIONS FROM SCHIFF BASES OF α-AMINO ESTERS; ENANTIOSELECTIVE SYNTHESIS OF α-ARYL AMINO ACIDS

We report here a convenient synthesis of α-substituted aryl amino acids via the addition of α-imino esters to fluorobenzene tricarbonylchromium complexes.Optically pure α-aryl amino acids have been prepared by enantioselective substitution of fluorobenzene complexes using Schiff bases of L-alanine, leucine and valine methyl esters and (1R,2R,5R)-2-hydroxypinan-3-one.